Thanks Kiefer Ipsen, and great question. I think one thing I would suggest is to still apply for those roles where you feel you can help. The industry, while more mature than when I entered 10 years ago, still doesn’t have a great grasp on what designers can offer. Thus, you see poorly written job postings or requests for people who can do it all.
When you apply, understand that they are likely still understanding how you can help them. They pick buzz words titles they here about not because they don’t believe in design but simply because they are new to the field. Us the interview process to ask them questions rather than sell yourself to the role they posted. As you ask them questions, their true needs will arise and you will be seen as a solution to their problems rather than a misfit for their current posted role.